ℍ𝕂-𝟞𝟝

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Joined 6 months ago
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Cake day: July 14th, 2024

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  • He’s a CS student, surely he could learn some hacking skills and access some internal communications that exposes illegal activity, no? That takes longer, but is probably more effective at actually sparking change than murder.

    It would be swept under the rug, maybe get prosecuted and fined for q token amount.

    There are three ways just off the top of my head that this improves the situation.

    It puts fear into the people murdering the masses through policy, other CEOs might think twice now.

    It makes people think and talk about this, and put the topic of healthcare CEOs being murderers into the public discourse.

    It showcases that public support, actually bipartisan public support exists for positive change, it’s just not on the ballot. Some smart politician might figure out how to ride that wave into office.





  • I’d add Digital Combat Simulator to Il-2, it’s not just that they are great sims, they pretty much are the only sims out there besides maybe Falcon.

    That said, game studios are getting out of Russia as well.

    One aspect that isn’t being discussed though is that Eastern European gaming culture very heavily favours PC gaming over consoles. My guess is that it’s because hackability / crackability is valued, and people are uses to have to make do with less. That’s also why a huge percentage of the piracy scene is from Eastern Europe and Russia specifically.

    Just look at how even a comparatively westernised studio like CDPR is doing with consoles. And how most of Eastern European games are hard-to-get-into, use-your-whole-keyboard titles.

    I’m just saying is that Russia deciding that they will do domestic consoles is about as braindead as if Afghanistan decided to do domestic subcompact EVs. Hard to start up an industry with very little domestic demand. I feel that the idea came from a bubble of privileged rich in Moscow who are largely separated from mainstream Russian culture.





  • No, it’s the conclusion of the paper cited in your source. The supposed proCoV2 is 3 base pairs away from Wuhan-1, and is 1100 base pairs away from other human-infecting SARS strains.

    Basically there was another similar virus that had the same spike proteins - if you remember the photos, the virus is a spiked ball, the antibodies bond to the spikes. It was a precursor to the Wuhan strain, so basically the fact that there were antibodies in Italy before the Wuhan outbreak just means that similar shit was going around the world before, but not the same shit.

    https://par.nsf.gov/servlets/purl/10287595

    Because proCoV2 is three bases different from the Wuhan-1 genome, we estimate that the divergence of the earliest variants of proCoV2 occurred 5.8–8.1 weeks earlier, based on the range of estimated mutation rates of coronavirus genomes (see Materials and Methods). This timeline puts the presence of proCoV2 in late October 2019, which is consistent with the report of a fragment of spike protein identical to Wuhan-1 in early December in Italy, among other evidence (Giovanetti et al. 2020; Li, Wang, et al. 2020; van Dorp et al. 2020; Amendola et al. 2021). The sequenced segment of the spike protein is short (409 bases). It does not span positions in which 49 major early variants were observed, which means that the Italian spike protein fragment can only confirm the existence of proCoV2 before the first coronavirus detection in China.

    I haven’t said anything about labs. Nobody treats the lab theory as a “proven fact”. But it is a proven fact that the specific strain that got dubbed COVID-19 first appeared in the general vicinity of Wuhan.


  • The first confirmed cases were in Wuhan, and right now, the state of science is that started either in Wuhan or near Wuhan. It’s complicated science because where antibodies were found is still just one datapoint, a precursor can have the same molecular structure on the virus surface, so similar or exactly the same antibodies. Meaning since the discussed proCoV2 was only three base pairs away, it could be producing the same antibodies, be widespread, infect, even kill people, yet not be COVID-19.

    The problem that the Chinese political system doesn’t promote open academic discussion - that the virus is political - doesn’t help either.


  • Same source says that it definitely came to Europe from China though, a few paragraphs lower:

    These findings do not at all suggest that the virus originated in Italy, but they endorse the idea that the virus was likely spreading in China before the first known cases and that could have been circulated by travelers given direct the connections between China and European and US countries, particularly the Northern West and East Italian regions, which are among the most industrialized and connected areas of Italy. Evidence used to support this hypothesis comes from a comparative genomic analysis of more than 175,000 genomes, which delineated 22 distinct SARS-CoV-2 haplogroups with a broad geographic distribution within China, pointing towards an early emergence and widespread cryptic circulation of the virus well before its isolation in January 2020 [25]. Recently, Kumar et al. reconstructed the mutational history of SARS-CoV-2 using a so called ‘mutation order approach’ (MOA) [26]. From their analysis of more than 174,000 genomes, major mutational fingerprints revealed that it is useful to identify and track the spatiotemporal evolution of novel coronavirus. The progenitor genome identified differed from that of the first coronaviruses sampled in China by three variants, implying that none of the earliest patients represents the index case or gave rise to all human infections. However, multiple coronavirus infections in China, the USA and Europe harbored the progenitor genetic fingerprint in January 2020 and later, suggesting that the progenitor was spreading worldwide months before.

    A recently published letter by Petti et al. summarizes existing evidence that corroborates the infectious disease epidemiology principle of pathogen circulation prior to the recognized outbreak [27]. The eventuality of an early SARS-CoV-2 circulation already relatively sustained in Europe and America is not so astonishing, as SARS-CoV-2 is mainly a respiratory pathogen. Therefore, a novel unknown respiratory virus responsible for severe pneumonia like SARS-CoV-2 could circulate undetected for months or years, be responsible for many deaths, and even become a pandemic, before peculiar characteristics of the disease are noticed that allow for its identification.

    Looks as if the original virus that definitely came from China caused less severe symptoms and was not detected, but still caused infections thus antibody findings.

    Did China do transparent peer-reviewed research into this?